Guanfacine ER (Intuniv ER)

Medication Information & Treatment Considerations

Guanfacine ER (Intuniv ER) is a prescription medication that may be considered by a licensed psychiatric provider as part of a treatment plan when clinically appropriate. Treatment recommendations are based on an individual’s symptoms, medical history, treatment goals, and overall clinical evaluation. Guanfacine works by affecting alpha-2 adrenergic receptors in the brain, which are involved in attention, impulse control, emotional regulation, and stress response. Individual experiences with medication vary, and treatment outcomes depend on many factors unique to each person. Guanfacine ER is not a controlled substance and must be prescribed by a licensed psychiatric provider. Through Telemynd, medication may be prescribed following a secure virtual evaluation when clinically appropriate. Many insurance plans cover guanfacine, and generic options are widely available. Some people may experience side effects such as drowsiness, fatigue, dizziness, dry mouth, low blood pressure, or headache. Your provider will monitor your response to treatment and make adjustments as needed.

Important Safety Information

Guanfacine may cause drowsiness, dizziness, low blood pressure, or changes in heart rate. Individuals beginning treatment should be monitored for side effects that could affect daily activities, including driving or operating machinery. This medication may not be appropriate for everyone. Before starting or changing any medication, discuss potential risks, benefits, side effects, warnings, and drug interactions with your healthcare provider. For complete prescribing information, medication warnings, precautions, contraindications, drug interactions, and the FDA-approved Medication Guide, please review the current FDA-approved prescribing information for guanfacine ER (Intuniv ER).

Educational Notice

This content is provided for informational and educational purposes only and should not be considered medical advice, treatment recommendations, or a guarantee that any medication will be prescribed. Medication decisions are made by licensed healthcare providers following a comprehensive clinical evaluation and consideration of individual needs.

Last reviewed: June 2026. Prescribing information may change. Refer to the current FDA-approved labeling for the most up-to-date safety information.